Epidural clonidine utilised as an adjunct to neighborhood anesthetics has three different mechanisms of action. First, the stimulation of alpha-two-receptors from the dorsal horn minimizes discomfort transmission. Next, clonidine could potentially cause neighborhood vasoconstriction that limitations vascular removal of nearby epidural anesthetics. Discover the implications for long te... https://thebookpage.com/story5222818/onolidine-fundamentals-explained