Summary: Cellular senescence irreversibly arrests cell proliferation. accompanied by a multi-component senescence-associated secretory phenotype (SASP) that participates in several age-related diseases. Using stable isotope labeling with amino acids (SILACs) and cultured cells. we identify 343 SASP proteins that senescent human fibroblasts secrete at 2-fold or higher levels compared w... https://www.socialstudiesscholar.com/