90% of ibuprofen is metabolised to inactive compounds within the liver, mostly by glucuronidation, to make two metabolites - a hydroxylated compound as well as a carboxylated compound. Evident quantity of distribution is 0.fourteen L/kg. Ibuprofen and its metabolites quickly cross the placental barrier in pregnant animals (rabbits and rats). https://aleistera701dgi6.mycoolwiki.com/user